Peer-reviewed veterinary case report
Horse diagnosed with acute myelomonocytic leukemia after surgery
By Spier, S J et al.·Published in Journal of the American Veterinary Medical Association·1986·View original on PubMed →
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Original publication title: Acute myelomonocytic leukemia in a horse.
- Species:
- horse
Plain-English summary
A 7-year-old Quarter Horse stallion was first seen for colic, which is severe abdominal pain, and had surgery to remove a stone from his intestines. After the surgery, he developed complications and was found to have low white blood cell and platelet counts. Five months later, he was brought back for swelling in his legs and to fix a hernia, and that’s when he was diagnosed with acute myelomonocytic leukemia, a type of blood cancer. Treatment with a specific medication did not help, and a post-mortem examination showed cancer spread in several organs. Unfortunately, the treatment was unsuccessful.
Abstract
A 7-year-old Quarter Horse stallion with a myeloproliferative disorder was examined because of colic, and an enterolith was removed surgically. The horse experienced secondary complications after abdominal surgery, and leukopenia and thrombocytopenia were detected. Five months later, the horse was examined for recurrent peripheral edema and for repair of an abdominal incisional hernia. Acute myelomonocytic leukemia was diagnosed, and treatment with low-dose (noncytocidal) cytosine arabinoside was unsuccessful. Necropsy revealed neoplastic infiltrate in the spleen, liver, lung, adrenal gland, testes, and eye. The persistent hematologic abnormalities before the onset of overt leukemia may represent hematopoietic dysplasia or preleukemia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/3458690/