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Peer-reviewed veterinary case report

Acute pancreatitis, azotaemia, cholestasis and haemolytic anaemia in a dog: a case report

Journal:
Veterinární Medicína
Year:
2013
Authors:
M. Guadarrama-Olhovich et al.
Affiliation:
Faculty of Veterinary Medicine and Husbandry, National Autonomous University of Mexico, Mexico City, Mexico · CZ
Species:
dog

Plain-English summary

This case involves a female Cocker Spaniel who developed acute pancreatitis, which is inflammation of the pancreas, along with several serious complications. She showed signs of kidney issues, liver problems, and anemia, which is a low red blood cell count, likely due to her immune system attacking her own red blood cells. The dog was also dehydrated and had been vomiting, which contributed to her electrolyte imbalances. Tests revealed various abnormalities in her blood and urine, indicating severe inflammation and damage to multiple organs. The treatment approach required careful consideration of her symptoms and test results, and while the report does not specify the outcome, it emphasizes the importance of thorough diagnosis and monitoring in such complex cases.

Abstract

We here report acute pancreatitis with multiorganic complications in a female Cocker Spaniel. The most important alterations in clinical pathology were renal azotaemia, hyperbilirubinaemia with a prevalence of conjugated bilirrubin and increased alkaline phosphatase by cholestasis; hyperamylasaemia due to pancreatitis; dehydration, hyponatraemia, hypochloraemia and hypokalaemia related to vomiting; metabolic acidosis and respiratory alkalosis corresponding to mixed acid-base disorder; markedly regenerative anaemia with spherocytes and agglutination due to immune-mediated haemolytic anaemia and intravascular haemolysis; leukocytosis with a left shift. Proteinuria, glucosuria, bilirubinuria and haemoglobinuria were detected in the urine. Severe suppurative pancreatitis with peripancreatic necrosis and suppurative esteatitis, tubulorrhectic nephrosis, severe hepatitis and intrahepatic cholestasis corresponded with alterations described by clinical pathology. In order to diagnose acute pancreatitis in dogs with multiple complications, it is very important to integrate the results of clinical pathology with the anamnesis and physical examination of the animal. It is especially important to note that the serum activity of amylase correlates with time after the pancreatic attack.

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Original publication: https://doi.org/10.17221/6657-VETMED