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Peer-reviewed veterinary case report

Dog died from kidney inflammation after surgery with halothane

By McNeil, P E·Published in The Veterinary record·1992·Department of Veterinary Pathology, United Kingdom·View original on PubMed

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Original publication title: Acute tubulo-interstitial nephritis in a dog after halothane anaesthesia and administration of flunixin meglumine and trimethoprim-sulphadiazine.

Species:
dog

Plain-English summary

A dog died four days after surgery for a hip problem, and a post-mortem examination revealed acute tubulo-interstitial nephritis, which is a type of kidney inflammation. The dog had received halothane anesthesia, flunixin meglumine for pain relief, and trimethoprim-sulphadiazine as an antibiotic during its treatment. The combination of these factors likely led to kidney failure. Unfortunately, despite the medical interventions, the dog did not survive.

People also search for: dog kidney failure after surgery · flunixin meglumine side effects in dogs · trimethoprim-sulphadiazine for dogs

Abstract

Acute tubulo-interstitial nephritis was diagnosed post mortem when a dog died four days after surgery for a femoral head resection. Possible causative factors associated with halothane anaesthesia, flunixin meglumine analgesia and prophylactic antibiotic therapy with trimethoprim-sulphadiazine are discussed. It is concluded that death was due to renal failure associated with tubulo-interstitial nephritis as a result of a combination of ischaemic and toxic events.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1413422/