Peer-reviewed veterinary case report
Allopurinol treatment helps imported dogs with leishmaniasis outside
By Helm, M et al.·Published in Schweizer Archiv fur Tierheilkunde·2013·Institut fü·View original on PubMed →
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Original publication title: [Allopurinol therapy in imported dogs with leishmaniasis treated outside the endemic area].
- Species:
- dog
Plain-English summary
A group of 31 dogs diagnosed with leishmaniasis, a travel-related infection, were treated with allopurinol, a medication often used for this condition. Many of these dogs showed symptoms like skin lesions, limping, or low energy, while others had abnormal lab results but no visible signs. After starting allopurinol, 20 of the dogs saw their symptoms improve significantly within 1 to 5 months. This treatment proved effective in managing the infection and helping the dogs feel better.
People also search for: dog leishmaniasis treatment · allopurinol for dogs · dog skin lesions · why is my dog limping · dog low energy symptoms
Abstract
Canine leishmaniosis (CL) has become one of the most frequently diagnosed travel associated infection in dogs in Switzerland and Germany. The aim of the study was to define recommendations for treatment with allopurinol and follow-up examinations of dogs with CL in a non endemic area. 31 dogs infected with Leishmania were treated with allopurinol (10 - 15 mg/kg twice daily, per os) and the effectiveness was examined. The diagnosis had been confirmed by the detection of specific anti-Leishmania antibodies and/or Leihmania-DNA. 22 dogs had clinical signs (skin lesions, lameness or lack of fitness) and 9 dogs were asymptomatic but showed abnormal laboratory parameters. Under treatment with allopurinol the symptoms disappeared within 1 - 5 months in 20 dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24091231/