Peer-reviewed veterinary case report
Large muscle tumor on a dog's front leg diagnosed by special testing
By J.K. Park et al.·Published in Veterinární Medicína·2016·College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea, CZ·View original on DOAJ →
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Original publication title: Alveolar rhabdomyosarcoma in a dog confirmed using myogenin immunohistochemistry: a case report
- Species:
- dog
Plain-English summary
A five-year-old male Maltese dog had a large mass removed from his right front leg, which was found to be an alveolar rhabdomyosarcoma, a type of cancer that originates from skeletal muscle. The mass measured 4 by 6 cm and was firm to the touch. After surgery, the tumor was examined under a microscope, revealing specific characteristics that confirmed the diagnosis. Unfortunately, the outcome of the treatment isn't mentioned, but surgical removal is often the first step in managing such tumors.
People also search for: Maltese dog leg mass · dog cancer treatment options · what is alveolar rhabdomyosarcoma in dogs
Abstract
A large mass from the right forelimb of a five-year-old, male, Maltese dog, was resected surgically and examined histopathologically. Grossly, the 4 × 6 cm mass was well-demarcated and firm. Microscopically, the mass was characterised by neoplastic mononuclear cells with large round hyperchromatic nuclei and scant cytoplasm. The neoplastic tumour cells were separated by thick or thin collagen septa and were arranged in an alveolar pattern forming cell nests. Immunohistochemical detections of the tumour revealed positive reactions for vimentin, desmin and myogenin, but the tumour was negative for alpha smooth muscle actin (α-SMA), S-100, CD3, CD79a, CD68, cytokeratin 8 (CK8) and cytokeratin 18 (CK18). These results showed that the tumour cells originated from skeletal muscle; therefore, the tumour was diagnosed as an alveolar rhabdomyosarcoma.
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Search related cases →Original publication on DOAJ: https://doi.org/10.17221/8882-VETMED