Peer-reviewed veterinary case report
Cat with jaw tumor invading bone and spreading to lymph node
By Nordio, Laura et al.·Published in Journal of comparative pathology·2023·San Marco Veterinary Clinic and Laboratory, Italy·View original on PubMed →
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Original publication title: Ameloblastic fibro-odontosarcoma with mandibular bone invasion and regional lymph node metastasis in a cat: case report.
- Species:
- cat
Plain-English summary
A 13-year-old neutered male cat was brought in with a growth in his mouth that was causing problems. A CT scan showed that the growth was invading the bone in his jaw and had spread to a lymph node in his neck. After testing the tissue, the vet diagnosed it as ameloblastic fibro-odontosarcoma, a rare type of tumor that can spread. This case highlights that even uncommon tumors in cats can have the potential to metastasize.
People also search for: cat mouth tumor · cat jaw growth · cat cancer treatment · cat lymph node swelling · cat oral tumor symptoms
Abstract
Odontogenic tumours are uncommon neoplasms in domestic animals, mostly solitary and locally infiltrative, but rarely metastatic. We report the case of a 13-year-old neutered male cat presented with a mandibular gingival neoformation. A computed tomography scan revealed an irregular neoformation with marked post-contrast enhancement, associated with lysis of the incisive bone and mandibular symphysis. Histologically, the oral mucosa and mandibular bone were infiltrated by a neoplasm consisting of a mixed population of odontogenic epithelium admixed with bundles of odontogenic ectomesenchyme, multifocally associated with hard tissue deposition. A spindloid cell component had metastasized to the right mandibular lymph node. The epithelial component was immunoreactive for cytokeratins (CK) 5/6, CK 14, pancytokeratin (CK AE1/AE3) and p63; the ectomesenchymal component was vimentin positive. A final diagnosis of ameloblastic fibro-odontosarcoma with bone invasion and lymph node metastasis was made. The findings indicate the metastatic potential of this rare tumour.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37913747/