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Peer-reviewed veterinary case report

Doberman with chronic eye membrane treated by amniotic transplant

By O'Leary, Louise et al.·Published in Veterinary ophthalmology·2018·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Amniotic membrane transplantation for ligneous conjunctivitis in a doberman.

Species:
dog

Plain-English summary

A 2-year-old female Doberman was brought in for severe eye problems, specifically chronic conjunctivitis that caused thick, opaque membranes over her eyes, making it hard to see. Despite trying anti-inflammatory and immunosuppressive medications, her condition didn't improve. The vet then surgically removed the membranes and used amniotic membrane to help heal the eye surfaces. Two years later, the dog showed no signs of the membranes returning, marking a successful treatment for her condition.

People also search for: dog eye problems · Doberman conjunctivitis treatment · amniotic membrane for dogs

Abstract

An approximately 2-year-old female Doberman Pinscher was referred for the evaluation of bilateral, chronic proliferative conjunctivitis. Ophthalmic examination revealed bilateral thick, opaque pseudomembranes originating from the conjunctivae that prevented visualization of the cornea and interior structures of the eye. Histopathological findings of biopsies of the pseudomembranes were consistent with ligneous conjunctivitis. Serum plasminogen activity levels were within the normal range. Treatment with topical and systemic anti-inflammatory and immunosuppressive drugs did not improve the conjunctival lesions. The pseudomembranes were surgically excised, and the conjunctival surfaces were reconstructed with amniotic membrane. At final re-examination two years postsurgery, there was no evidence of recurrence of the pseudomembranes. To the authors' knowledge, this is the first reported case of the successful treatment of canine ligneous conjunctivitis with amniotic membrane transplantation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29482261/