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Peer-reviewed veterinary case report

Dog with chronic fungal skin disease causing nose deformity

By de Souza Suguiura, Igor Massahiro et al.·Published in Veterinary research communications·2024·17 Regional de Sa&#xfa, Brazil·View original on PubMed

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Original publication title: An atypical case of chronic paracoccidioidomycosis in a dog caused by a fungus from the Paracoccidioides brasiliensis complex.

Species:
dog

Plain-English summary

A 5-year-old mixed-breed dog was brought in with a severe skin problem that caused a deforming lesion on its nose. This unusual case of paracoccidioidomycosis, a fungal infection more common in humans, showed a different immune response than typically seen in dogs. The vet identified the specific fungus causing the issue and noted that it resembled cases found in people. Understanding this case could help improve diagnosis and treatment for similar infections in dogs.

People also search for: dog nose skin lesion · fungal infection in dogs · paracoccidioidomycosis treatment for dogs

Abstract

Paracoccidioidomycosis (PCM) is a systemic mycosis endemic in Latin American countries and one of the most important fungal diseases regarding incidence and mortality in humans. PCM has also been described in some animal species such as dogs. In this study we describe a new case of PCM disease in a dog that differed from previous records in the literature which includes a progressive evolution of fungal dermatitis causing a deforming lesion in the nose, like those found in human patients, and humoral response against gp70 instead of gp43, the major diagnostic antigen for human PCM. The clinical isolate through the ITS and partial gp43 gene phylogenetic analysis was grouped in the Paracoccidioides brasiliensis complex. This case describes several features which may contribute to improving diagnosis and understanding of canine paracoccidioidomycosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38758425/