Peer-reviewed veterinary case report
An In Vivo Compression Model of Spinal Cord Injury.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2018
- Authors:
- Paterniti, Irene et al.
- Affiliation:
- Department of Chemical · Italy
Abstract
Animal spinal cord injury (SCI) models have proven highly useful for investigating the mechanisms involved in the injury process and evaluating the effectiveness of experimental therapeutic interventions. Over the last years, substantial improvements have been made in producing consistent and reproducible animal SCI models. Different SCI models have been developed to address the mechanism of injury, being divided into contusion, compression, distraction, dislocation, transection, or chemical models. The method described here is a mouse compression model of SCI that, in many respects, faithfully reproduces SCI in man.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29222797/