Peer-reviewed veterinary case report
An introduction to metabolomics and its potential application in veterinary science.
- Journal:
- Comparative medicine
- Year:
- 2007
- Authors:
- Jones, Oliver A H & Cheung, Victoria L
- Affiliation:
- Department of Biochemistry · United Kingdom
Plain-English summary
Metabolomics is a scientific approach that looks at the small molecules in living organisms to understand various biological processes. It has been used in many areas, like studying how genes work, checking for toxins, and even in nutrition. While this method is becoming popular in human medicine to test new drugs safely, it hasn't been widely used in veterinary research yet. The authors of this study introduce metabolomics and talk about how it could be beneficial for veterinary science in the future. Overall, they highlight its potential to improve research while also reducing costs and the number of animals needed for studies.
Abstract
Metabolomics has been found to be applicable to a wide range of fields, including the study of gene function, toxicology, plant sciences, environmental analysis, clinical diagnostics, nutrition, and the discrimination of organism genotypes. This approach combines high-throughput sample analysis with computer-assisted multivariate pattern-recognition techniques. It is increasingly being deployed in toxico- and pharmacokinetic studies in the pharmaceutical industry, especially during the safety assessment of candidate drugs in human medicine. However, despite the potential of this technique to reduce both costs and the numbers of animals used for research, examples of the application of metabolomics in veterinary research are, thus far, rare. Here we give an introduction to metabolomics and discuss its potential in the field of veterinary science.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17974125/