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Peer-reviewed veterinary case report

Anal sac gland cancer in 64 cats in the UK from 1995-2007

By Shoieb, A M & Hanshaw, D M·Published in Veterinary pathology·2009·Department of Pathology·View original on PubMed

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Original publication title: Anal sac gland carcinoma in 64 cats in the United kingdom (1995-2007).

Species:
cat

Plain-English summary

A group of 64 cats in the UK were diagnosed with anal sac gland carcinoma, a type of cancer that affects the glands near the anus. Most of these cats were Domestic Shorthairs, and they ranged in age from 6 to 17 years, with an average age of 12. Unfortunately, the prognosis was poor; more than three-quarters of the cats either had to be euthanized or died from the cancer, with a median survival time of just 3 months. This highlights the seriousness of anal sac gland tumors in cats and the need for early detection and treatment.

People also search for: cat anal sac cancer symptoms · Domestic Shorthair cancer treatment · cat cancer survival rates

Abstract

A retrospective study was performed to characterize 64 cases of anal sac gland carcinoma (ASGC) in cats. All ASGCs diagnosed between 1995 and 2007 at a private diagnostic laboratory in the UK were reviewed. Apocrine gland origin was confirmed in a subset of these tumors by immunohistochemistry and the use of the glandular cytokeratin antibody (CAM 5.2). Associated clinical, gross, and histologic features were compared with those of canine ASGC. Anal sac gland carcinoma accounted for 0.5% of all feline skin neoplasms. Thirty-nine of the cats with ASGC were female, with a female male ratio of 1.56. Fifty-two (81.1%) of the 64 tumors were in Domestic Shorthair cats, 5 (7.8%) in Siamese, 3 (4.8%) in Domestic Longhair, 2 (3.1%) in Burmese, and 1 (1.6%) each in a Birman and a Persian cat. Significant differences in prevalence of ASGC among breeds were not detected. Cats ranged in age from 6 to 17 years (median and mean age, 12 years). More than three quarters of the affected cats for which postsurgical outcome was known were euthanatized or died as a direct consequence of the neoplasm, with a median survival of 3 months. Survival rates at 1 and 2 years were 19 and 0%, respectively.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19276061/