Peer-reviewed veterinary case report
Risk factors for poor outcome in dogs with cluster seizures
By Cagnotti, Giulia et al.·Published in Frontiers in veterinary science·2020·Department of Veterinary Science, Italy·View original on PubMed →
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Original publication title: Analysis of Early Assessable Risk Factors for Poor Outcome in Dogs With Cluster Seizures and Status Epilepticus.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought to the vet after experiencing cluster seizures, which are multiple seizures occurring in a short period. The study found that dogs who had their first seizure outside the typical age range, had a high temperature when they arrived, and had not previously received anti-seizure medications were more likely to have a poor outcome. Understanding these risk factors can help veterinarians better manage dogs experiencing these serious seizure episodes. Treatment options may vary, but timely intervention is crucial for improving outcomes in affected dogs.
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Abstract
Status epileptics (SE) and cluster seizures (CS) are serious neurological emergencies associated with poor outcome in epileptic patients. Data on risk factors associated with outcome in epileptic patients affected by CS and SE have not been studied extensively to date. In the present retrospective study potential risk factors predictive of negative outcome in a population of dogs affected by CS and SE were analyzed. Ninety-three dogs were included in the study: 21/93 patients (23%) presented with SE and 72/93 (77%) with CS. Based on multivariate statistical analysis, factors statistically associated with a poor outcome were the occurrence of the first epileptic seizure outside the defined idiopathic interval (6 months-6 years), a condition of hyperthermia at presentation and the absence of previous antiepileptic drugs (AEDs) in case of previous history of seizures. The results of the present study implement data on risk factors associated with poor outcome in dogs affected by CS or SE and can aid in the creation of anscoring system, similar to systems currently applied in human medicine upon hospital admission to benchmark performances and establish protocols for triage and therapeutic management.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33195572/