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Peer-reviewed veterinary case report

Risk factors for poor outcome in dogs with cluster seizures or status

By Giulia Cagnotti et al.·Published in Frontiers in Veterinary Science·2020·Department of Veterinary Science, University of Turin, Grugliasco, Italy, CH·View original on DOAJ

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Original publication title: Analysis of Early Assessable Risk Factors for Poor Outcome in Dogs With Cluster Seizures and Status Epilepticus

Species:
dog

Plain-English summary

A 5-year-old mixed-breed dog was brought in for severe seizures, specifically cluster seizures and status epilepticus, which are serious neurological emergencies. The study looked at 93 dogs and found that certain factors, like having their first seizure outside the typical age range, having a high temperature when they arrived, and not having been on any seizure medications before, were linked to worse outcomes. Understanding these risk factors can help veterinarians better manage and treat dogs experiencing these types of seizures.

People also search for: dog cluster seizures treatment · status epilepticus in dogs · dog seizure first aid

Abstract

Status epileptics (SE) and cluster seizures (CS) are serious neurological emergencies associated with poor outcome in epileptic patients. Data on risk factors associated with outcome in epileptic patients affected by CS and SE have not been studied extensively to date. In the present retrospective study potential risk factors predictive of negative outcome in a population of dogs affected by CS and SE were analyzed. Ninety-three dogs were included in the study: 21/93 patients (23%) presented with SE and 72/93 (77%) with CS. Based on multivariate statistical analysis, factors statistically associated with a poor outcome were the occurrence of the first epileptic seizure outside the defined idiopathic interval (6 months−6 years), a condition of hyperthermia at presentation and the absence of previous antiepileptic drugs (AEDs) in case of previous history of seizures. The results of the present study implement data on risk factors associated with poor outcome in dogs affected by CS or SE and can aid in the creation of an ad hoc scoring system, similar to systems currently applied in human medicine upon hospital admission to benchmark performances and establish protocols for triage and therapeutic management.

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Original publication on DOAJ: https://doi.org/10.3389/fvets.2020.575551