Peer-reviewed veterinary case report
Survival factors for cats with injection-site sarcomas after tumor
By Romanelli, Giorgio et al.·Published in Journal of the American Veterinary Medical Association·2008·Clinica Veterinaria Nerviano, Italy·View original on PubMed →
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Original publication title: Analysis of prognostic factors associated with injection-site sarcomas in cats: 57 cases (2001-2007).
- Species:
- cat
Plain-English summary
A group of 57 cats with injection-site sarcomas (tumors that can develop at vaccination sites) was studied to understand factors affecting their survival. It was found that cats with higher-grade tumors (grade 3) were more likely to develop distant metastasis, which is when the cancer spreads to other parts of the body. Local recurrence of the tumors did not have clear factors associated with it. The study suggests that cats with grade 3 tumors may benefit from additional treatments like chemotherapy to help prevent the cancer from spreading.
People also search for: cat injection-site sarcoma prognosis · cat cancer treatment options · signs of cancer in cats
Abstract
OBJECTIVE: To identify prognostic factors in cats with injection-site sarcomas (ISSs). DESIGN: Retrospective case series. ANIMALS: 57 cats with ISSs. PROCEDURES: Medical records of cats were reviewed with regard to sex, age, anatomic site of tumor, tumor size, histologic grade, excision of a primary tumor versus excision of a recurrent ISS, use of excision alone versus excision plus adjuvant therapy, local tumor recurrence, and development of distant metastasis to predict overall survival time (ie, time from tumor excision to death). RESULTS: In univariate analyses, local recurrence and development of distant metastasis were significantly associated with survival time in cats. On multivariate analysis, development of distant metastasis remained a significant prognostic factor. Histologic grade was associated with distant metastasis, with cats having grade 3 tumors being significantly more likely to develop metastasis than cats with grade 1 and 2 tumors. Factors associated with local recurrence of ISSs were not identified. CONCLUSIONS AND CLINICAL RELEVANCE: The development of distant metastasis, which may occur later during the course of the disease, was identified as a prognostic factor for overall survival time in cats with ISSs. In addition, cats with histologic grade 3 ISSs should be considered for further interventional studies with chemotherapy to prevent the high rate of distant metastasis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18412533/