Peer-reviewed veterinary case report
Survival rates for dogs with different kidney disease types
By Schultz, Devyn M et al.Ā·Published in Journal of veterinary internal medicineĀ·2025Ā·Department of Veterinary Pathobiology, United StatesĀ·View original on PubMed ā
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Original publication title: Analysis of survival among biopsy-determined categories of kidney disease in dogs.
- Species:
- dog
Plain-English summary
A study looked at 649 dogs diagnosed with kidney disease to understand how different types of kidney problems affect survival. The results showed that dogs with renal amyloidosis had the shortest survival time, averaging just 76 days, while those with focal segmental glomerulosclerosis (FSGS) lived about 536 days on average. Factors like age and certain blood test results also influenced how long the dogs lived after their diagnosis. This information can help veterinarians provide better care and treatment options based on the specific type of kidney disease a dog has.
People also search for: dog kidney disease survival rates Ā· renal amyloidosis in dogs Ā· FSGS treatment for dogs
Abstract
BACKGROUND: There are many causes of kidney disease in dogs. The association of the diagnostic category with survival is unknown. OBJECTIVE: Determine survival outcomes for biopsy-determined diagnostic categories of kidney disease in dogs. ANIMALS: Six hundred forty-nine dogs were biopsied for evaluation of kidney disease. METHODS: Retrospective study. Survival information was obtained for dogs whose kidney biopsy was submitted to the International Veterinary Renal Pathology Service between 2008 and 2018. Signalment, serum creatinine (sCr), urine protein : creatinine ratio (UPCR), and serum albumin (sAlb) were reported at the time of biopsy. Cox proportional hazards analysis was performed for the 14 categories with >10 cases having follow-up to determine hazard ratios (HR), using focal segmental glomerulosclerosis (FSGS) as baseline. RESULTS: The median survival time (MST) for all dogs with follow-up (n = 649) was 608 days (interquartile range [IQR]: 109-1475 days). The most follow-up was obtained for FSGS (n = 138, MST 536 days). Dogs with renal amyloidosis (n = 80) had the shortest survival (MST 76 days, IQR 8-299 days) and, in the multivariate analysis including age, sCr, sAlb, and UPCR, an increased risk of death (HR 1.79 [95% CI: 1.22-2.65], P < .01). Dogs with podocytopathy, membranous glomerulonephritis (MGN), mixed MGN, membranoproliferative GN (MPGN), and mixed MPGN had decreased risk of death. Regardless of category, increasing age, sCr, and UPCR and decreased sAlb were associated with a greater risk of death. CONCLUSIONS: The diagnostic category is associated with survival in dogs with kidney disease. Survival of individual dogs within each category was highly variable.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39925194/