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Peer-reviewed veterinary case report

Anaplasmosis infection and blood changes in two dogs in France

By Domingos, Margarida Canelas et al.·Published in Veterinary clinical pathology·2011·Laboratoire Vebiotel, France·View original on PubMed

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Original publication title: Anaplasmosis in two dogs in France and molecular and phylogenetic characterization of Anaplasma phagocytophilum.

Species:
dog

Plain-English summary

Two dogs in France were found to have a tick-borne infection called Anaplasmosis, which can cause serious health issues. They showed signs like low platelet counts and changes in their white blood cells. The infection was confirmed through a special test that detects the bacteria's genetic material. Fortunately, with proper treatment, these dogs can recover, but it's important for pet owners to be aware of the risks of tick bites and to consult their veterinarian if they notice any unusual symptoms.

People also search for: dog tick disease symptoms · Anaplasmosis treatment for dogs · why is my dog bleeding from low platelets

Abstract

Two dogs in France were diagnosed with Anaplasma phagocytophilum infection by real-time PCR. The most remarkable hematologic and biochemical findings were severe thrombocytopenia, mild neutrophilia, morulae in neutrophils, and increased serum concentration of the α2-globulin fraction detected by agarose gel electrophoresis of serum proteins. Using sequencing of the partial 16S rRNA and ankA genes, molecular characterization of the A. phagocytophilum strains showed that the organisms from both dogs were identical to the European strains isolated from horses and people. Based on phylogenetic analysis, the ankA gene was more discriminating than the 16S rRNA gene in distinguishing the majority of European and American strains of A. phagocytophilum infecting people and animals. Three isolates of A. phagocytophilum, 1 from Spain (cow) and 2 from Norway (sheep and deer), were external to the European and American clades.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21554371/