Peer-reviewed veterinary case report
French Bulldog with brain tumor spreading after radiation and chemo
By Nakamoto, Yuya et al.·Published in The Journal of veterinary medical science·2018·Kyoto Animal Referral Medical Center, Japan·View original on PubMed →
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Original publication title: Anaplastic oligodendroglioma with leptomeningeal dissemination in a french bulldog.
- Species:
- dog
Plain-English summary
A 2.5-year-old male French Bulldog was brought in for seizures, and an MRI showed a brain tumor called a glioma. The dog received radiation therapy and ongoing chemotherapy, which initially helped shrink the tumor. However, months later, follow-up imaging showed that the cancer had spread to the membranes around the brain, causing fluid buildup. Unfortunately, due to the poor prognosis, the dog was euthanized about a year after diagnosis. This case highlights the need for ongoing monitoring in dogs with brain tumors, even after treatment.
People also search for: French Bulldog seizures · dog brain tumor treatment · glioma in dogs · dog euthanasia after cancer
Abstract
A 2.5-year-old male French Bulldog was evaluated for seizures. Cranial magnetic resonance imaging (MRI) suggested a glioma in the left piriform area. Radiation therapy (RT) and continuous chemotherapy were administered. Although the lesion had regressed significantly 2 months after RT, a follow-up MRI revealed meningeal enhancement in the left piriform area, which expanded further, with hydrocephalus, by day 310 (8 months after RT). Because of the poor prognosis, the dog was euthanized on day 356 and necropsy was performed. Histopathological examination confirmed anaplastic oligodendroglioma with leptomeningeal dissemination. This case suggests that the possibility of leptomeningeal dissemination and hydrocephalus should be considered even after RT and chemotherapy for anaplastic oligodendroglioma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30185721/