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Peer-reviewed veterinary case report

Animal models to evaluate bacterial biofilm development.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2014
Authors:
Thomsen, Kim et al.
Affiliation:
Department of Clinical Microbiology

Abstract

Medical biofilms have attracted substantial attention especially in the past decade. Animal models are contributing significantly to understand the pathogenesis of medical biofilms. In addition, animal models are an essential tool in testing the hypothesis generated from clinical observations in patients and preclinical testing of agents showing in vitro antibiofilm effect. Here, we describe three animal models - two non-foreign body Pseudomonas aeruginosa biofilm models and a foreign body Staphylococcus aureus model.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24664830/