Peer-reviewed veterinary case report
Caracal with eye inflammation revealing large granular lymphoma
By Aitken-Palmer, Copper et al.·Published in Veterinary ophthalmology·2011·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Anterior uveitis as an atypical presentation of large granular lymphoma in a caracal (Caracal caracal).
Plain-English summary
An 11-year-old female caracal was brought to the vet after experiencing three months of not eating, vomiting, and losing weight. During the exam, the vet noticed eye problems, including inflammation and uneven pupil size. Further tests revealed that the caracal had a rare type of cancer called large granular lymphoma, which was affecting her eye and intestines. Unfortunately, despite the diagnosis, the caracal's condition was severe, and she did not survive. This case highlights the importance of considering lymphoma in cats with eye inflammation.
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Abstract
An 11-year-old, female, spayed caracal (Caracal caracal) presented with a 3-month history of intermittent anorexia, vomiting, and weight loss. At examination, bilateral anterior uveitis with anisocoria was present. Further examination under general anesthesia revealed the anterior chamber of the right eye contained copious amounts of thick fibrin, hypopyon, and hyphema obscuring the ventral pupil margin and ventral iris. Aqueous paracentesis revealed a cytologic diagnosis of large granular lymphoma. Additional antemortem diagnostics (computed tomography, ultrasound with fine needle aspiration, and cytology) confirmed the diagnosis of multicentric large granular lymphoma with associated intestinal perforation. Necropsy and histopathology confirmed multicentric large granular lymphoma in the right eye, jejunum, mesenteric lymph nodes, and right kidney. Large granular lymphoma in nondomestic felids is likely rare since it has not been previously reported, but should be considered as a differential in any felid species with anterior uveitis or when lymphoma is considered. In the case of this caracal, the use of aqueous paracentesis with cytology was a powerful diagnostic.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21929612/