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Peer-reviewed veterinary case report

Dog developed heart muscle disease after epirubicin chemotherapy

By Lee, Ye-Rin et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2015·Department of Veterinary Internal Medicine, South Korea·View original on PubMed

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Original publication title: Anthracycline-induced cardiomyopathy in a dog treated with epirubicin.

Species:
dog

Plain-English summary

An 8-year-old American cocker spaniel was diagnosed with dilated cardiomyopathy, a heart condition that can cause symptoms like weakness and difficulty breathing. This condition developed after the dog received multiple rounds of chemotherapy, including a drug called epirubicin, to treat lymphoma four years earlier. The heart issue was linked to the toxicity of the chemotherapy. Unfortunately, the dog’s heart condition is a serious side effect of the treatment received for cancer.

People also search for: dog heart problems after chemotherapy · cocker spaniel dilated cardiomyopathy · epirubicin side effects in dogs

Abstract

An 8-year-old American cocker spaniel dog was diagnosed with dilated cardiomyopathy. Four years earlier, the dog had been diagnosed with multicentric lymphoma and had received 4 cycles of multi-agent chemotherapy, including doxorubicin and epirubicin. The total cumulative dose of epirubicin was 168 mg/m(2). Dilated cardiomyopathy was considered a consequence of epirubicin toxicity.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26028676/