Peer-reviewed veterinary case report
Anti-ulcerogenic lignans from Taxus baccata L.
- Journal:
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- Year:
- 2004
- Authors:
- Gurbuz, Ilhan et al.
- Affiliation:
- Gazi University
- Species:
- rodent
Abstract
Four lignan type compounds, lariciresinol, taxiresinol, isolariciresinol and 3-demethyl-iso-lariciresinol, were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through chromatographic techniques. In vivo anti-ulcerogenic potency of these compounds was investigated on ethanol-induced ulcerogenesis model in rats at two different doses, 50 and 100 mg/kg. All compounds were shown to possess significant anti-ulcerogenic activity at both doses. However, the effect of taxiresinol was the most prominent.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15241933/