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Peer-reviewed veterinary case report

Assessing motor development and function in mouse models of neurodevelopmental disorders.

Journal:
Methods in cell biology
Year:
2024
Authors:
Dierdorff, Lauren et al.
Affiliation:
Icahn School of Medicine at Mount Sinai · United States

Abstract

Alterations in motor development often accompany neurodevelopmental disorders (NDD) and can have an impact on social interaction and communication. Studying motor development and function in mouse models of NDDs can offer a window to identify underlying biological mechanisms and establish preclinical outcome measures for testing therapeutics. This chapter describes tests to measure motor developmental milestones early postnatally and adult motor functions in mouse models of NDDs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38880523/