Peer-reviewed veterinary case report
Puppy diet fat sources linked to epilepsy risk in Finnish dogs
By Hemida, Manal et al.·Published in Frontiers in veterinary science·2023·Department of Equine and Small Animal Medicine·View original on PubMed →
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Original publication title: Assessing the association between supplemented puppyhood dietary fat sources and owner-reported epilepsy in adulthood, among Finnish companion dogs.
- Species:
- dog
Plain-English summary
A study found that feeding fish fat to puppies at least once a week may help reduce the risk of epilepsy later in life. Researchers looked at 108 dogs with epilepsy and compared them to 397 dogs without the condition, analyzing their diets during puppyhood. The results suggested that those who had fish fat in their diet were less likely to develop epilepsy as adults. While the findings are promising, they recommend further studies to confirm the link between fish fat and epilepsy prevention.
People also search for: dog epilepsy prevention diet · puppy food fish fat · how to help my dog with seizures
Abstract
INTRODUCTION: Epilepsy is a serious and common neurological condition in dogs, despite the wide number of antiepileptic drugs available, in approximately one third of the patients, epilepsy remains unsatisfactorily controlled. We aim to analyze whether feeding dietary fat sources during puppyhood was associated with canine epilepsy in adulthood. METHODS: A nested case-control study was compiled from the validated DogRisk food frequency questionnaire (DogRisk FFQ). DogRisk FFQ collected feeding, disease, and background data about the dog. The study sample consisted of 108 owner-reported epileptic cases and 397 non-epileptic controls. Each case was matched with up to four controls for the key confounding factors of sex, breed, and age. We analyzed associations between feeding as a puppy and owner-reported epilepsy as an adult dog using Cox regression. We tested 55 different food variables. RESULTS: We found that feeding fish fat from dietary sources at least once a week during puppyhood was inversely associated with epilepsy in later life in the unadjusted analysis [OR 0.46 (95% CI 0.25-0.83),=0.01], while when adjusting for keeping conditions and dog characteristics the association was [OR 0.45 (95% CI 0.23-0.88),=0.02]. When adjusted for keeping conditions, dog characteristics, and other feeding factors, the association was of similar magnitude but not significance [OR 0.56 (95% CI 0.27-1.15),=0.12]. DISCUSSION: The study indicates possible protective associations of feeding the dog with dietary sources of fish fat against epilepsy, although the result could be confounded by other feeding factors. Findings are compatible with current knowledge regarding the role of omega-3 fatty acids and ketogenic diet, a low carbohydrate, high fat diet as supportive treatments of epilepsy. As our findings are based on observations, we suggest the possibility of causality but do not prove it. Dietary intervention studies should now be conducted to confirm our findings.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37781290/