Peer-reviewed veterinary case report
Pseudoplacentational endometrial hyperplasia linked to pyometra
By Santana, Clarissa H et al.·Published in Journal of comparative pathology·2020·Universidade Federal de Minas Gerais, Brazil·View original on PubMed →
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Original publication title: Association of Pseudoplacentational Endometrial Hyperplasia and Pyometra in Dogs.
- Species:
- dog
Plain-English summary
A study found that many female dogs with uterine inflammation also had a condition called pseudoplacentational endometrial hyperplasia (PEH), which is a type of abnormal thickening of the uterine lining. In fact, 79.4% of the dogs examined had PEH, and this condition was significantly linked to pyometra, a serious infection of the uterus. The research suggests that these conditions should be recognized separately rather than grouped together. If your dog shows signs of a possible uterine infection, such as lethargy, increased thirst, or unusual discharge, it's important to consult your veterinarian for proper diagnosis and treatment.
People also search for: dog pyometra symptoms · female dog uterine infection treatment · what is pseudoplacentational endometrial hyperplasia
Abstract
Uterine inflammation is the most common and clinically relevant genital change in bitches. The aim of this study was to evaluate the association between uterine hyperplasic lesions and uterine inflammation. Uteri and ovaries from 200 bitches were sampled after elective or pathological ovariohysterectomy and histologically evaluated. Endometrial hyperplastic lesions were classified as cystic endometrial hyperplasia (CEH) or pseudoplacentational endometrial hyperplasia (PEH), whereas cases of uterine inflammation were subdivided into endometritis or pyometra. The frequency of PEH (79.4%) was significantly higher (P <0.05) than CEH (20.6%), whereas 17.5% of the animals did not have any endometrial hyperplasic lesions. There was a statistically significant association between the frequency of PEH and uterine inflammation (P <0.0001) and PEH was also significantly associated with pyometra (P <0.05). There was no significant association between CEH and uterine inflammation. There was a significant association between dioestrus and the frequencies of PEH, CEH, uterine inflammation and pyometra. However, there was no significant association between endometritis and dioestrus. These results support the recommendation that the terms 'cystic endometrial hyperplasia', 'pseudoplacentational endometrial hyperplasia' and 'pyometra' should be used separately, instead of the classical term 'cystic endometrial hyperplasia-pyometra complex'.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33222878/