Peer-reviewed veterinary case report
Association of Veterinary Hematology and Transfusion Medicine (AVHTM) transfusion reaction small animal consensus statement (TRACS). Part 3: Diagnosis and treatment.
- Journal:
- Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
- Year:
- 2021
- Authors:
- Odunayo, Adesola et al.
- Affiliation:
- Department of Small Animal Clinical Sciences · United States
Plain-English summary
This study aimed to create clear guidelines for diagnosing and treating reactions that can happen when dogs and cats receive blood transfusions. Researchers reviewed existing literature and developed specific questions to guide their findings. They created 14 guidelines and four treatment plans based on the evidence they found, and there was strong agreement among experts on these recommendations. However, the study also highlighted that there are still many areas where more research is needed in veterinary blood transfusion practices. Overall, the guidelines can help veterinarians better manage transfusion reactions in pets.
Abstract
OBJECTIVE: To systematically review available evidence to develop guidelines for diagnosis and treatment of transfusion-associated reactions in dogs and cats. DESIGN: Standardized and systemic evaluation of the literature (identified through Medline via PubMed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. The available evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. The evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines, diagnostic, and treatment algorithms were generated based on the evaluation of the evidence. Consensus on the final guidelines was achieved through Delphi-style surveys. Draft recommendations were disseminated through veterinary specialty listservs for review and comments, which were evaluated and integrated prior to final publication. RESULTS: Medline via PubMed and Google Scholar databases were searched. There were 14 Population Intervention Comparison Outcome questions identified and corresponding worksheets were developed focusing on the diagnosis and treatment of transfusion-associated reactions in dogs and cats. Fourteen guidelines and four algorithms were developed with a high degree of consensus. CONCLUSIONS: This systematic evidence evaluation process yielded recommended diagnostic and treatment algorithms for use in practice. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/33751797/