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Peer-reviewed veterinary case report

B-cell lymphoma in dog with ehrlichiosis and histoplasmosis

By Brunker, Jill D & Hoover, John P·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2007·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: B-cell lymphoma in a dog with ehrlichiosis (Ehrlichia canis) and systemic histoplasmosis (Histoplasma capsulatum).

Species:
dog

Plain-English summary

A mixed breed dog being treated for ehrlichiosis (a tick-borne infection) and systemic histoplasmosis (a fungal infection) developed low platelet levels that wouldn't improve. When the vet found an abdominal mass, they performed surgery and biopsies, which revealed that the dog had B-cell lymphoma, a type of cancer. The lymphoma may have been linked to the ongoing inflammation caused by the other infections. Unfortunately, the outcome of the treatment isn't specified, but this case highlights the potential complications of chronic infections in dogs.

People also search for: dog ehrlichiosis treatment · mixed breed dog lymphoma symptoms · systemic histoplasmosis in dogs

Abstract

A mixed breed dog treated for ehrlichiosis and systemic histoplasmosis developed a refractory thrombocytopenia. When an abdominal mass was detected, exploratory laparotomy and biopsies confirmed lymphoma, which on immunohistochemical stains was determined to be of B-cell origin. Conceivably, the B-cell lymphoma in this dog was associated with chronic inflammation from ehrlichiosis, histoplasmosis, or both.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17436907/