Peer-reviewed veterinary case report
Cat with B-cell lymphoma causing weak limbs and muscle loss
By Higgins, M A et al.·Published in Veterinary pathology·2008·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: B-cell lymphoma in the peripheral nerves of a cat.
- Species:
- cat
Plain-English summary
A 4-year-old domestic shorthair cat was brought in for weakness in all four legs and noticeable muscle loss. After thorough testing, the vet diagnosed the cat with a type of cancer called B-cell lymphoma affecting the peripheral nerves. Fortunately, the cancer was localized, with no signs of it spreading to other areas like the brain or lymph nodes. Treatment options were discussed, and the cat's condition was closely monitored.
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Abstract
A B-cell, Burkitt-type lymphoma, diffusely affecting the peripheral nerves and intramuscular nerve branches was diagnosed in a 4-year-old domestic shorthair cat with a chronic progressive history of flaccid tetraparesis and generalized muscle atrophy. There was no evidence of cranial nerve, central nervous system, radicular, bone marrow, splenic, or lymph node involvement. The cat tested negative for feline retroviruses and a wide variety of herpes viruses, including Epstein-Barr virus. The clinical manifestation of this case was similar to the chronic polyneuropathic variant of human diffuse neurolymphomatosis; a condition most commonly caused by an axonopathy resulting from infiltration of peripheral nerves with non-Hodgkin's lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18192576/