Peer-reviewed veterinary case report
Bactericidal efficacy of ABI-0043, a novel rifamycin, in a murine pneumococcal pneumonia model.
- Journal:
- The Journal of antibiotics
- Year:
- 2006
- Authors:
- Lee, Su Young et al.
- Affiliation:
- Hartford Hospital · United States
Abstract
Novel rifamycins such as ABI-0043, ABI-0369, and ABI-0699 had comparable in vivo bactericidal activity with ceftriaxone against a penicillin-G-resistant, mefA-positive Streptococcus pneumoniae in a murine pneumonia model. ABI-0043 demonstrated a dose-dependent response with a high correlation to bacterial kill (+0.1 to -3.7 log 10CFU).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17323649/