Peer-reviewed veterinary case report
Oral bleeding in 4-month-old female Ba-Shar puppy with Basset Hound
By Christopherson, Pete W et al.·Published in Veterinary clinical pathology·2016·Department of Pathobiology, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Basset Hound thrombopathia in a 4-month-old female Ba-Shar (Sharp Asset).
- Species:
- dog
Plain-English summary
A 4-month-old female Ba-Shar puppy (a mix of Basset Hound and Shar Pei) was brought to the vet for bleeding from her mouth after losing baby teeth. She had previously experienced oral bleeding due to a cracked molar and had been hospitalized for over 24 hours to control the bleeding. Despite normal blood tests, further DNA testing revealed she had a genetic disorder called Basset Hound thrombopathia, which affects blood clotting. This case is notable as it marks the first diagnosis of this condition in a designer breed.
People also search for: puppy bleeding from mouth · Ba-Shar dental issues · Basset Hound thrombopathia treatment
Abstract
A 3-month-old female Basset Hound-Shar Pei mix puppy (Ba-Shar or Sharp Asset) presented with oral bleeding due to a cracked molar. On physical exam, an aural hematoma was also noted that the owner indicated was chronic. The puppy was hospitalized for over 24 h until the bleeding was brought under control. At 4 months of age, the puppy again presented with oral bleeding due to loss of deciduous teeth and was hospitalized until bleeding was controlled. Coagulation screening tests, platelet numbers, and von Willebrand Factor antigen levels were within reference limits. Based on the presence of platelet-type bleeding in the face of normal screening test results, samples were submitted for DNA testing for Basset Hound thrombopathia. The puppy tested as affected for the calcium and diacylglycerol regulated guanine nucleotide exchange factor I (CalDAG-GEFI) mutation causing this disorder. This is the first time thrombopathia has been diagnosed in a "designer" breed.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27037855/