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Peer-reviewed veterinary case report

Benign fibrous histiocytoma of prepuce in the mule.

Journal:
Reproduction in domestic animals = Zuchthygiene
Year:
2004
Authors:
Rapisarda, G et al.
Affiliation:
Dipartimento di Sanit&#xe0 · Italy

Plain-English summary

A 7-year-old mule was diagnosed with a benign tumor called a fibrous histiocytoma located on its prepuce (the sheath covering the penis). The tumor was removed through surgery, and tests showed that it was made up of specific types of cells that are not cancerous. This type of tumor is not commonly seen in mules, and the case adds to the limited information available in veterinary literature. The treatment was successful in removing the tumor.

Abstract

Here we present a case of preputial benign fibrous histiocytoma in a 7-year-old mule. This case was treated surgically. Pathologic analysis and diagnosis of these lesions were based on a combination of light microscopy and immunohistochemistry. Histologically, the tumour was composed primarily of a storiform pattern of fibroblastic and poligonal cells. In immunohistochemistry, except for consistent immunoreactivity for vimentin, nearly all tumour cells were positive for CD68, S-100 protein, pan-cytokeratin, alpha-smooth muscle actin, and desmin. Benign fibrous histiocytoma of the prepuce in mule is rarely reported in veterinary literature.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15129924/