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Peer-reviewed veterinary case report

Bilateral colobomas in a horse.

Journal:
Journal of comparative pathology
Year:
1989
Authors:
Schuh, J C
Affiliation:
Department of Veterinary Pathology · Canada
Species:
horse

Plain-English summary

An 8-year-old Quarterhorse mare was found to have bilateral true colobomas, which are gaps in the eye structure, along with cysts located near her optic nerves. She had been experiencing progressive blindness, which means her vision was getting worse over time. The colobomas happened because a part of her eye didn't develop properly during her early growth, and the cysts formed as a result of this issue. The exact cause of some changes in her optic nerves and retina is unclear; they could either be due to a developmental problem or damage over time. Overall, the findings highlight serious eye issues that have led to her vision loss.

Abstract

Bilateral true colobomas with retrobulbar cysts located over the optic nerves are described in an 8-year-old Quarterhorse mare with a history of progressive blindness. Colobomas result from the failure of an embryonic fissure to close and retrobulbar cysts result from eversion of the neuroectoderm through the colobomas. It could not be determined whether the small optic nerves and the scars, rosettes and disorganization of the cell layers in the retina were the result of concurrent dysplasia or were secondary to degeneration.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/2723162/