Peer-reviewed veterinary case report
Biochemical changes in dogs with large Babesia infection in Warsaw
By Zygner, W et al.·Published in Polish journal of veterinary sciences·2007·Department of Preclinical Sciences·View original on PubMed →
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Original publication title: Biochemical abnormalities observed in serum of dogs infected with large Babesia in Warsaw (Poland).
- Species:
- dog
Plain-English summary
A group of dogs in Warsaw infected with a parasite called Babesia showed various health issues, including liver and kidney problems. Many of these dogs had elevated liver enzymes and creatinine levels, indicating liver and kidney stress, while some also had low blood sugar and protein levels. These biochemical changes were linked to the severity of their illness. Treatment for Babesia typically involves medications to eliminate the parasite and supportive care for the affected organs. With appropriate treatment, many dogs can recover from this serious infection.
People also search for: dog Babesia infection symptoms · elevated liver enzymes in dogs · treatment for dog kidney problems
Abstract
Biochemical abnormalities observed in canine babesiosis are related to the severity of the disease. The primary biochemical abnormalities found in affected dogs are: increase of the serum activity of transaminases and alkaline phosphatase, azotemia, and hypoglycemia. The purposes of this study were: 1) to estimate biochemical abnormalities in dogs infected with large Babesia in Warsaw and 2) to evaluate statistically changes observed during canine babesiosis in dogs from Warsaw. Samples of serum were collected from dogs naturally infected with large Babesia. Among 2023 positive samples, 202 were randomly selected. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), total serum protein (TSP), albumin and blood glucose concentration were determined with a clinical chemistry analyser. Elevated activity of ALT, AST and ALP was detected accordingly in: 64.9, 92.6 and 31.7% of dogs. Elevated creatinine concentration and BUN were detected accordingly in 30.7 and 62.4% of dogs. Decrease of TSP, albumin, BUN, and hypoglycemia was detected accordingly in: 19.8, 32.7, 1.5 and 18.3% of dogs. The most common biochemical abnormalities found in affected dogs were: increase of activity of transaminases and ALP, elevated creatinine concentration, hypoalbuminemia and hypoglycemia. These abnormalities resulted from hepatopathy, renal failure and fasting.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18198540/