Peer-reviewed veterinary case report
Osteosarcoma in dog toe and paw bones - behavior and treatment
By Tremolada, Giovanni et al.·Published in Veterinary and comparative oncology·2021·Colorado State University, United States·View original on PubMed →
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Original publication title: Biological behaviour of primary osteosarcoma of the digits, metacarpal and metatarsal bones in dogs.
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog was diagnosed with osteosarcoma (a type of bone cancer) affecting the bones in its toes and feet. This type of cancer is rare in these areas but seems to have a better outlook than osteosarcoma in other parts of the body. The dog received treatment that included chemotherapy, and the average survival time for dogs with this condition was about 687 days. While the study suggests that dogs with osteosarcoma in these specific bones may live longer than those with it in other locations, more research is needed to confirm these findings and the benefits of chemotherapy.
People also search for: dog osteosarcoma treatment · dog bone cancer prognosis · chemotherapy for dog osteosarcoma
Abstract
Osteosarcoma (OSA) arising from the digits, metatarsal and metacarpal bones is rare and may carry a better prognosis compared with other locations. The aim of this study was to retrospectively evaluate the biological behaviour, the progression free interval (PFI), the survival time (ST) and evaluate the effect of adjuvant chemotherapy for OSA affecting these bones. Medical records from two academic institutions were reviewed and 15 cases were included. Descriptive statistics were used for signalment and history. For estimation of median PFI and median ST, the Kaplan-Meier method was utilized. The prognostic effect of chemotherapy, lymphocyte and monocyte count was investigated. Log-rank analysis was used to compare PFI and ST between groups. The overall median PFI and median ST were 377 and 687 days, respectively. No significant differences were noted for any of the variables evaluated. In this study, dogs affected by OSA of digits, metacarpal and metatarsal bones appear to have a longer ST compared with dogs with OSA of other appendicular locations. A study with a larger number of patients is needed to confirm these results and investigate the potential benefit of adjuvant chemotherapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32893971/