Peer-reviewed veterinary case report
Biomarkers in canine inflammatory bowel disease diagnostics.
- Journal:
- Polish journal of veterinary sciences
- Year:
- 2013
- Authors:
- Wdowiak, M et al.
- Affiliation:
- Department of Clinical Diagnostics
- Species:
- dog
Plain-English summary
Canine inflammatory bowel disease (IBD) is a group of long-lasting digestive disorders in dogs, but the exact cause is still unknown. Diagnosing IBD can be complicated and expensive because veterinarians have to rule out other illnesses that can cause similar symptoms. This article discusses the search for specific markers that could help make diagnosing IBD easier and more accurate. It covers recent findings on laboratory tests and certain markers that can be seen under a microscope, as well as insights from human IBD research that might be useful for dogs. Overall, the goal is to improve how we diagnose this condition in dogs.
Abstract
Canine inflammatory bowel disease (IBD) is a heterogeneous group of chronic gastrointestinal disorders. The etiology, similar to human IBD, remains unknown. Canine IBD is diagnosed by exclusion, which is a long, time and money-consuming process due to the need of elimination of other diseases presenting with similar symptoms. Therefore, a search for a specific and sensitive marker is needed to overcome these difficulties. The article is divided into 3 sections presenting up-to-date information about laboratory markers, immunohistochemical markers and changes in the neurochemical coding of the enteric nervous system, concentrating on their usefulness and future applications. Data concerning laboratory and immunohistochemical markers is based mainly on canine IBD, while the neuroimmunohistochemistry section presents knowledge from human IBD due to the lack of such studies in veterinary medicine.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24195302/