Peer-reviewed veterinary case report
Dog with aggressive natural killer cell leukemia died after 10 days
By Bonkobara, Makoto et al.·Published in Veterinary journal (London, England : 1997)·2007·Department of Veterinary Clinical Pathology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Blastic natural killer cell leukaemia in a dog--a case report.
- Species:
- dog
Plain-English summary
A 5-year-old male mixed-breed dog was diagnosed with a type of blood cancer called blastic natural killer cell leukemia after showing signs of illness. Despite receiving chemotherapy, the dog's condition worsened, and he sadly passed away just 10 days after being brought to the vet. This type of leukemia is known to have a poor prognosis in both dogs and humans.
People also search for: dog blood cancer symptoms · canine leukemia treatment · why is my dog sick and weak
Abstract
A case of canine non-T, non-B lymphoid leukaemia was determined to be of natural killer (NK) cell lineage by detecting specific expression of canine CD56 mRNA by reverse transcriptase polymerase chain reaction analysis. Although NK cells are usually considered to be morphologically large granular lymphocytes, the malignant NK cells in this case were agranular and blast-like, resembling human blastic NK cell leukaemia. The prognosis of human NK cell leukaemia is usually poor. In this case, the dog died 10 days after initial presentation, despite chemotherapy.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17113799/