Peer-reviewed veterinary case report
Dog became very tired and feverish after febantel causing bone marrow
By Petronzio, Abbey et al.·Published in Frontiers in veterinary science·2025·MSPCA-Angell, United States·View original on PubMed →
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Original publication title: Bone marrow toxicity associated with febantel administration in a dog: Case Report.
- Species:
- dog
Plain-English summary
A 6-year-old neutered male Labrador Retriever was brought to the vet because he was lethargic and had a fever 15 days after taking a medication called febantel. Blood tests showed he had low blood cell counts, and a bone marrow sample indicated it was not producing enough cells, likely due to the febantel. After stopping the medication, the dog fully recovered in about two weeks.
People also search for: dog lethargy after medication · febantel side effects in dogs · dog bone marrow suppression treatment
Abstract
INTRODUCTION: The objective of this case report is to describe a case of bone marrow suppression suspected to be secondary to febantel administration in a dog. CASE SUMMARY: A 6-year-old neutered male Labrador Retriever was presented for lethargy and fever 15 days after receiving oral febantel. Pancytopenia was noted, and bone marrow sampling was consistent with hypoplasia suspected to be due to the febantel administration as no other toxic insults were identified. The dog made a full recovery in approximately 2 weeks after stopping the febantel. DISCUSSION: This is the first report of suspected bone marrow toxicity secondary to febantel administration. Febantel is metabolized to fenbendazole, which has been documented as causing bone marrow toxicity in canines.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40260210/