Peer-reviewed veterinary case report
Canine and feline retinal lymphoma: a retrospective review of 12 cases.
- Journal:
- Veterinary ophthalmology
- Year:
- 2017
- Authors:
- Malmberg, Jennifer L et al.
- Affiliation:
- Department of Microbiology · United States
Plain-English summary
This study looked at 12 pets, including 6 dogs and 6 cats, that had a type of cancer called ocular lymphoma, which affected their retinas but not much else in their eyes. The researchers wanted to understand the characteristics of this cancer and how it compares to similar cases in humans. They found that this specific type of retinal lymphoma is quite rare, making up about 1% of all eye lymphomas in dogs and cats. The average age of the affected pets was around 7 years for dogs and 11 years for cats, with no specific breeds or genders being more likely to develop this condition. Most of the cases were identified as a subtype called diffuse large B-cell lymphoma, while a few were classified as peripheral T-cell lymphoma.
Abstract
This retrospective study identified 12 cases (6 canine and 6 feline) of ocular lymphoma with extensive retinal involvement and relative sparing of other ocular tissues. Our objectives were to describe the morphologic and immunohistochemical features of retinal lymphoma, assess the degree of correlation to the human counterpart, assign subtypes based on the veterinary-adapted WHO classification system, and promote accurate reporting of retinal involvement in cases of intraocular lymphoma. Our findings suggest that a distinct retinal tropism is quite rare, representing approximately 1% of all cases of canine and feline ocular lymphoma. No breed or sex predispositions were identified. The mean age of the affected animal was 7 years (range 4-10) and 11 years (range 6-19) for dogs and cats, respectively. Nine cases (5 canine and 4 feline) were classified as diffuse large B-cell lymphoma (DLBCL) subtype. The remaining cases were classified as peripheral T-cell lymphoma (PTCL).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26868476/