Peer-reviewed veterinary case report
Dog with ulcers in stomach and skin from histiocytic syndrome
By V. Revajova et al.·Published in Veterinární Medicína·2004·University of Veterinary Medicine, Kosice, Slovak Republic, CZ·View original on DOAJ →
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Original publication title: Canine histiocytic syndrome manifested as ulcerative gastroenterocolitis, skin lesions and lymphadenopathy - a case report
- Species:
- dog
Plain-English summary
A 7-year-old female boxer was diagnosed with histiocytic syndrome, which caused severe gastrointestinal issues, skin lesions, and swollen lymph nodes. The dog had multiple ulcers in her stomach and intestines, along with two large ulcerated masses on her skin. Unfortunately, the condition was serious, and the diagnosis was confirmed through a necropsy after the dog passed away. This case highlights the importance of recognizing symptoms like skin lesions and gastrointestinal distress in dogs, as they can indicate serious underlying health problems.
People also search for: boxer dog skin lesions · dog gastrointestinal ulcers · histiocytic syndrome in dogs
Abstract
Histiocytic syndrome was diagnosed in a 7-year-old boxer bitch using histological and immunohistochemical methods. Necropsy confirmed the presence of enlarged superficial lymph nodes, two large ulcerated oval cutaneous masses one on the left lateral thoracic wall and one near to the vulva. In the gastrointestinal tract there were multiple ulcers apparently overlying nodules located in the submucosa of stomach, ulcers in the ileocaecal valve, and enlargement of lymphoid nodules in the small intestine manifested ulcerative gastroenteritis. Histologically, the thoracic wall mass showed infiltration of the tissue by macrophages with cytoplasmic vacuoles. The vacuoles contained PAS-positive polysaccharides. The macrophages were positive for alpha-1-antitrypsin and lysozyme by immunostaining. Lysozyme is a marker for phagocytic macrophages/histiocytes and may be used to confirm cells of this lineage in cases when there is any doubt.
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Search related cases →Original publication on DOAJ: https://doi.org/10.17221/5710-VETMED