Peer-reviewed veterinary case report
Protein in urine in an 8-year-old Dachshund linked to IgA kidney
By Yabuki, Akira et al.·Published in The Journal of veterinary medical science·2016·Joint Faculty of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Canine IgA nephropathy: a case report.
- Species:
- dog
Plain-English summary
An 8-year-old spayed female Miniature Dachshund was brought in because she had severe protein in her urine, which is a sign of kidney issues. She had been on long-term medication for other health problems. After a kidney biopsy, the vet found a specific type of kidney disease similar to one seen in humans. They stopped her previous medication and started her on a new drug called enalapril, which helped reduce the protein in her urine. Now, she is doing well and has not had any further issues.
People also search for: Miniature Dachshund kidney disease · dog protein in urine treatment · enalapril for dogs
Abstract
Immunoglobulin (Ig) A nephropathy is a rare form of canine glomerular disease. This report describes a case of canine IgA nephropathy showing characteristics typical of human IgA nephropathy. An 8-year-old, spayed female Miniature Dachshund showed persistent severe proteinuria without azotemia. She was receiving long-term glucocorticoid therapy due to chronic gastritis and an intra-abdominal suture granuloma. A renal biopsy demonstrated mesangial proliferative glomerulonephritis with predominantly mesangial IgA deposition and electron-dense deposits in the paramesangium. These findings closely resembled those of human IgA nephropathy. Glucocorticoid treatment was discontinued, and the angiotensin-converting enzyme inhibitor enalapril was administrated as an antiproteinuric agent. The proteinuria subsequently went into remission, and the patient has maintained good condition without recurrence.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26596464/