Peer-reviewed veterinary case report
Leishmania infantum infection in two Labrador retrievers with skin
By Binhazim, A A et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·1992·Department of Pathology, United States·View original on PubMed →
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Original publication title: Canine leishmaniasis caused by Leishmania leishmania infantum in two Labrador retrievers.
- Species:
- dog
Plain-English summary
A 5-year-old male Labrador retriever was diagnosed with canine leishmaniasis, a serious parasitic disease, after showing symptoms like weight loss, lack of appetite, fever, and skin lesions. The dog had a history of travel to areas where the disease is common. Tests revealed kidney issues and high protein levels in the blood. Treatment options for leishmaniasis can vary, but early diagnosis and management are crucial for improving the dog's health.
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Abstract
Canine leishmaniasis, a generally fatal parasitic disease, was diagnosed in 2 dogs with a medical history of foreign travel, lymphadenopathy, emaciation, anorexia, intermittent fever, and cutaneous lesions. Clinically, hyperproteinemia, proteinuria, azotemia, and glomerulopathy were evident. Isolation of Leishmania species was done using Schneider's Drosophila medium. Syrian hamsters were used for infectivity studies. Clear taxonomic identification was done biochemically by isoenzyme analysis and comparison of zymogram banding patterns with 6 World Health Organization reference strains. Based on the geographic origin of affected dogs, clinicopathologic presentation, visceralization with hepatosplenomegaly in hamsters, and isoenzyme analysis, a diagnosis of Leishmania leishmania infantum was made. This study, representing the first taxonomic identification of an isolate from canine leishmaniasis, demonstrates the zoonotic and epidemiologic implications of this disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1515492/