Peer-reviewed veterinary case report
Mandibular bone cancer in dogs and survival after treatment
By Straw, R C et al.·Published in Journal of the American Animal Hospital Association·1996·Department of Clinical Science, United States·View original on PubMed →
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Original publication title: Canine mandibular osteosarcoma: 51 cases (1980-1992).
- Species:
- dog
Plain-English summary
A group of 51 dogs with jaw tumors called mandibular osteosarcomas were treated with different methods, including surgery, chemotherapy, and radiation. Most dogs underwent surgery to remove part of the jaw, and those treated with surgery alone had a one-year survival rate of about 71%. The overall survival rate for all dogs was around 59.3%. The study found that the type of treatment didn't significantly affect survival, but the tumor's characteristics did play a role in predicting how long the dogs would live after treatment.
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Abstract
Fifty-one dogs treated for mandibular osteosarcomas (OSs) were studied retrospectively. Treatments were partial mandibulectomy (n = 32); partial mandibulectomy and chemotherapy (n = 10); partial mandibulectomy and radiation therapy (n = 3); partial mandibulectomy, radiation therapy, and chemotherapy (n = 4); and radiation therapy alone (n = 2). The overall one-year survival rate was 59.3%. Dogs treated with surgery alone had a one-year survival rate of 71%, which is higher than the one-year survival rate for dogs with appendicular OSs treated with surgery alone (p of 0.001 or less; hazard ratio of 0.29). There was no apparent effect of various treatment modalities, nor institution where treatment was given, nor histological type. Histological score and, to a lesser extent, histological grade were predictive of survival outcome.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8731141/