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Peer-reviewed veterinary case report

Signs and symptoms of multicentric lymphoma in middle-aged dogs

By Dobson, J. M. & Gorman, N. T.·Published in Journal of Small Animal Practice·1993·View original on Crossref

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Original publication title: Canine multicentric lymphoma 1: Clinico‐pathological presentation of the disease

Species:
dog
LymphomaDrinking & peeingDogs

Plain-English summary

A 6-year-old male dog was diagnosed with multicentric lymphoma after showing swollen lymph nodes and other symptoms like increased thirst and urination. This type of cancer is common in middle-aged dogs and often leads to widespread disease by the time it's detected. Many affected dogs also had blood abnormalities, such as low platelet counts and anemia. Treatment options typically include chemotherapy, which can help manage the disease and improve quality of life, but the prognosis varies based on the stage at diagnosis.

People also search for: dog lymphoma symptoms · swollen lymph nodes in dogs · canine cancer treatment options

Abstract

ABSTRACTThe clinicopathological features of 90 cases of canine multicentric lymphoma are described. The majority of cases occurred in middle‐aged dogs (five to eight years of age) with a mean age at presentation of 6–7 years. A marked sex predisposition was noted with male dogs out numbering females by 2:1. No significant breed predispositions were found. The most common presentation was a generalised lymphadenopathy but in approximately one‐third of the cases this was accompanied by other signs including polyuria and polydipsia, facial oedema and upper respiratory tract obstruction. Approximately two‐thirds of all the cases showed non‐specific haematological abnormalities including thrombocytopenia, anaemia and white blood cell anomalies. All the cases were clinically staged according to the anatomical extent of the disease. The majority of the dogs were classified as stage 3 or above, denoting that the disease is invariably widespread or systemic upon initial presentation.

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Original publication on Crossref: https://doi.org/10.1111/j.1748-5827.1993.tb02584.x