Peer-reviewed veterinary case report
Myxosarcoma tumors in 32 dogs - surgery and outcomes
By Iwaki, Yoshimi et al.·Published in BMC veterinary research·2019·The Department of Clinical Science, United States·View original on PubMed →
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Original publication title: Canine myxosarcomas, a retrospective analysis of 32 dogs (2003-2018).
- Species:
- dog
Plain-English summary
A group of 32 dogs diagnosed with myxosarcoma, a type of soft tissue tumor, underwent surgery to remove the tumors. Some dogs received additional treatments like radiation or chemotherapy, while others did not. The average survival time for these dogs was about 2 years, but it varied based on the tumor's characteristics. Unfortunately, about 41% of the dogs experienced a return of the tumor within a few months, and 25% developed metastasis, spreading to nearby lymph nodes or lungs. Overall, myxosarcoma tends to have a higher chance of coming back compared to other similar tumors.
People also search for: dog myxosarcoma treatment · soft tissue tumor in dogs · dog tumor recurrence rate
Abstract
BACKGROUND: Myxosarcomas are known to be classified as soft tissue sarcomas. However, there is limited clinical characterization pertaining specifically to canine cutaneous myxosarcomas in the literature. The objective of this study is to evaluate the local recurrence rate, metastatic rate and prognosis of canine myxosarcoma. RESULTS: A total of 32 dogs diagnosed with myxosarcoma via histopathology were included in this retrospective study. All dogs had surgical resection. No adjunct treatments were performed in 9 dogs, while 22 dogs also received either radiation therapy or chemotherapy, or a combination of both. One dog received only NSAID after surgery. Overall median survival time (MST) was 730 days (range 20-2345 days). The MST of dogs with a tumor mitotic count < 10/10 HPF was 1393 days (range 20-2345 days). The dogs with a tumor mitotic count of 10 or greater/10 HPF had a MST of 433 days (range 169-831 days). There was no significant difference of MST among different treatment modalities. Local recurrence was noted in 13 cases (40.6%) and the median time to recurrence was 115.5 days (range 50-1610 days). The median time to local recurrence in dogs with mitotic count of < 10/10 HPF was 339 days (range 68-1610 days) and in dogs with mitotic count of 10 or greater/10 HPF was 119 days (range 50-378). Metastasis to local lymph node or lung was noted in 8 cases (25%) with median time to metastasis of 158.5 days (range 0-643 days). CONCLUSIONS: Based on the results of this retrospective study, myxosarcoma may have a higher local recurrence rate and risk of metastasis to the local lymph nodes compared to other soft tissue sarcomas.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31248415/