Peer-reviewed veterinary case report
Dog with swollen neck lymph nodes
By Ricci, G et al.·Published in Medical mycology·2004·Department of Pathology, Brazil·View original on PubMed →
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Original publication title: Canine paracoccidioidomycosis.
- Species:
- dog
Plain-English summary
A female adult Doberman developed swollen lymph nodes in her neck, which led her owner to seek veterinary care. After a biopsy, the vet found that she had a serious fungal infection called paracoccidioidomycosis (PCM). This is the first known case of PCM in a dog, and the diagnosis was confirmed through specialized tests. Unfortunately, the abstract does not provide information on the treatment or outcome for this dog.
People also search for: Doberman swollen lymph nodes · dog fungal infection treatment · paracoccidioidomycosis in dogs
Abstract
Paracoccidioidomycosis (PCM) is a severe disease caused by the dimorphic fungus Paracoccidioides brasiliensis, which is characterized by granulomatous pulmonary and systemic lesions, affecting mainly men between 20 and 60 years of age. Reports of PCM disease in animals are rare, but the disease has been described in armadillos. On the other hand, PCM infection of domestic and wild animals detected by serological or cutaneous tests in the absence of apparent disease has been frequently reported. We present here the case of a female adult Doberman that developed cervical lymphadenomegaly. Histopathological examination of a cervical biopsy specimen revealed active PCM, with an epithelioid, granulomatous inflammation containing numerous yeast-like, multiple budding fungal forms. The diagnosis of PCM was confirmed by immunohistochemistry using a specific antibody anti-gp43 and by nested PCR using primers for the amplification of the gp43 gene region. This is the first report of PCM disease occurring in a dog, an animal that has been shown to play an important role in the natural history of North American blastomycosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15473365/