Peer-reviewed veterinary case report
Canine parvo viral enteritis in dogs: Diagnostic and therapeutic evaluation
- Journal:
- Journal of Veterinary and Animal Sciences
- Year:
- 2023
- Authors:
- G. Shruti & K. Ajay
- Affiliation:
- Veterinary officer, Veterinary Hospital-Bah Ki Dhar, Distt. Mandi, Himachal Pradesh, India, · IN
- Species:
- dog
Plain-English summary
In a study involving 110 dogs with symptoms of enteritis (inflammation of the intestines), researchers in India found that 48 of them tested positive for Canine Parvovirus (CPV), a serious viral infection. They used a rapid test called Scanvet to diagnose the dogs and confirmed the results with a more detailed test called PCR. The dogs that tested positive were divided into groups and treated with different combinations of standard care, immunomodulators (like Vitamin E and Selenium), and an antiviral medication called Oseltamivir. The results showed that the dogs receiving the additional treatments had a better recovery, with less vomiting and diarrhea, and they were less likely to die from the infection. Overall, the combination of standard treatment with immunomodulators and Oseltamivir showed promising results in helping dogs recover from Parvoviral enteritis.
Abstract
A total of 110 dogs presented to Teaching Veterinary Clinical Complex, CSKHPKV, Palampur (H.P.), India with the history of enteritis/gastroenteritis were screened for Canine Parvovirus (CPV). Out of these 110 dogs, 48 dogs were found positive for CPV by using Scanvet - a rapid antigen detection kit. All the 110 samples were subjected to Polymerase Chain Reaction (PCR) to check whether there were some cases that were false positive or false negative by Scanvet. Positive cases were, then, divided into 4 groups of 12 dogs each, with 4 different treatment regimens followed for each group. In addition to standard treatment protocol, our study tested effect of immunomodulators (Vitamin E & Selenium) and antiviral “Oseltamivir” on recovery of dogs. This type of study (using Oseltamivir and immunomodulators) was not done previously in the state and hence, our aim was to test whether this treatment increases survivability and recovery rate for dogs with Parvoviral enteritis in Himachal Pradesh. Groups containing immunomodulators were more efficacious than their counterparts without immunomodulators. Addition of Oseltamivir and immunomodulators to standard therapy resulted in reduced mortality, cessation of diarrhoea and vomiting earlier than routine therapy. Scanvet diagnostic kit was found to be a quick alternate method for diagnosis of Parvo Viral Enteritis. Overall, the group treated with antibiotic+ supportive+ symptomatic+ antiviral treatment along with immunomodulator displayed promising results.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://doi.org/10.51966/jvas.2023.54.1.71-78