Peer-reviewed veterinary case report
Canine parvovirus type 2 vaccine protects dogs from type 2c infection
By Spibey, N et al.·Published in Veterinary microbiology·2008·Intervet UK Ltd, United Kingdom·View original on PubMed →
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Original publication title: Canine parvovirus type 2 vaccine protects against virulent challenge with type 2c virus.
- Species:
- dog
Plain-English summary
A group of vaccinated beagle puppies were tested to see if they could resist a serious virus called canine parvovirus type 2c. The puppies received their vaccinations at 8-10 weeks old and were monitored after being exposed to the virus. The vaccinated puppies showed no signs of illness and did not spread the virus, while the unvaccinated puppies became sick and shed the virus in their feces. This study confirms that the vaccine effectively protects dogs against this dangerous virus.
People also search for: dog parvovirus vaccine effectiveness · beagle puppy vaccination schedule · canine parvovirus symptoms
Abstract
The ability of dogs vaccinated with a live attenuated CPV type 2 (Nobivac Intervet) vaccine to resist challenge with a current CPV2c isolate was investigated. Six SPF beagle dogs were given the minimum recommended course of vaccination, comprising a single inoculation of vaccine (Nobivac Lepto+Nobivac Pi) at 8-10 weeks of age followed 3 weeks later with a parvovirus vaccine in combination with distemper, adenovirus and parainfluenza virus (Nobivac DHPPi) and a repeat leptospirosis vaccine. Six control dogs were kept unvaccinated. All animals were challenged orally with a type 2c isolate of CPV and monitored for clinical signs, virus shedding, white blood cell fluctuations and serological responses. All vaccinated dogs were fully protected; showing no clinical signs nor shedding challenge virus in the faeces, in contrast to control animals, which displayed all the typical signs of infection with pathogenic CPV and shed challenge virus in the faeces.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18006253/