Peer-reviewed veterinary case report
Canine renal failure syndrome in three dogs.
- Journal:
- Journal of veterinary science
- Year:
- 2006
- Authors:
- Jeong, Won Il et al.
- Affiliation:
- Department of Veterinary Pathology · South Korea
- Species:
- dog
Plain-English summary
Three dogs that had died were examined at a veterinary college to understand what happened to them. Before they passed away, all three dogs showed signs of being very thin, not eating, being depressed, and having severe vomiting and diarrhea for about a week to ten days. These symptoms started about a month after they were fed certain commercial dog foods. During the examination after death, the dogs had serious kidney damage and unusual green-yellow stones in their kidneys, along with bleeding in various organs, which might have been caused by kidney failure. While the findings suggested that a toxin affected their kidneys, the exact cause of this toxicity couldn't be identified.
Abstract
Three dead dogs were brought to the College of Veterinary Medicine, Kyungpook National University for study. Clinically, all the dogs showed emaciation, anorexia, depression, hemorrhagic vomiting and diarrhea for 7-10 days before death. All the clinical signs were first noted for about one month after feeding the dogs with commercial diets. At necropsy, all 3 dogs had severe renal damage with the same green-yellowish colored nephroliths in the renal pelvis. They also showed systemic hemorrhage and calcification of several organs, which might have been induced by uremia. Microscopically, necrosis, calcification and calculi were detected in the renal tubules, and especially in the proximal convoluted tubules and collecting ducts of the kidney. These findings were supportive of a mycotoxic effect, and especially on their kidneys. However, the precise cause of the toxic effect in these cases of canine renal failure could not be determined.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16871028/