Peer-reviewed veterinary case report
Signs and survival in dogs with small clear cell T-zone lymphoma
By Martini, V. et al.·Published in Veterinary and Comparative Oncology·2015·Department of Veterinary Sciences and Public Health University of Milan Milan Italy, Italy·View original on Crossref →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Canine small clear cell/T‐zone lymphoma: clinical presentation and outcome in a retrospective case series
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with a rare type of lymphoma called small clear cell/T-zone lymphoma were observed to understand their symptoms and outcomes. Most of these dogs were at an advanced stage of the disease when they were brought in, but many did not show obvious signs of illness. While some dogs had a good chance of long-term survival, a few unfortunately passed away quickly or developed other cancers. The study highlights the need for more research to find out which dogs might be at higher risk for complications.
People also search for: dog lymphoma symptoms · small clear cell lymphoma in dogs · canine cancer prognosis · Golden retriever lymphoma · dog cancer treatment options
Abstract
AbstractPublished studies, taken together, suggest the existence of a single canine lymphoma entity, with a small clear cell appearance by cytological evaluation, a histopathological T‐zone pattern and an aberrant CD45‐negative T‐cell phenotype, mostly characterized by long‐term survival. We describe clinical presentation and outcome in a retrospective case series of canine small clear cell/T‐zone lymphoma. Despite the reported predisposition of Golden retriever, this breed was not represented in our case series. Most dogs presented with stage V disease, whereas only few had clinical signs or peripheral cytopenias. Blood was almost always more infiltrated than bone marrow. Median survival confirmed the favourable prognosis described in literature, but a few dogs died within a short time. Also, a subgroup of dogs developed second malignancies, eventually leading to death. We did not investigate possible prognostic factors because of the wide variety in treatments, and further studies are needed to identify high‐risk animals.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Crossref: https://doi.org/10.1111/vco.12155