Peer-reviewed veterinary case report
Canine visceral leishmaniasis in dogs from São Paulo Brazil
By Marcili, Arlei et al.·Published in Vector borne and zoonotic diseases (Larchmont, N.Y.)·2020·Department of Medicine and Animal Welfare, Brazil·View original on PubMed →
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Original publication title: Canine Visceral Leishmaniasis in São Paulo, Brazil, the Most Populous City of South America: Isolation, Molecular Diagnosis, and Phylogenetic Inferences.
- Species:
- dog
Plain-English summary
A group of 201 dogs in São Paulo, Brazil, were tested for canine visceral leishmaniasis, a serious disease that can be transmitted to humans. Out of these dogs, 10 were found to have the disease through traditional testing, while a more sensitive molecular test identified 50 dogs as positive. This highlights the importance of regular testing and monitoring for this disease, especially in urban areas where it can spread easily. The study suggests that better surveillance and prevention measures are needed to protect both dogs and humans from this zoonotic disease.
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Abstract
Canine visceral leishmaniasis affects dogs, the main urban reservoirs, which favor the transmission and expansion of this zoonotic disease in areas with high anthropization process and human density. We investigated the occurence ofbased in molecular diagnosis, and phylogenetic analysis of isolates obtained from dogs in metropolitan region of São Paulo.A total of 201 dogs were tested by parasitological and molecular diagnosis. Phylogenetic analysis based sequences from SSUrDNA and gGAPDH genes were performed.The parasitological diagnosis revealed 5% (10/201) of positivity, and the sequences obtained from seven isolates were clustered with L.in phylogentic analysis based on SSUrDNA and gGAPDH genes. A total of 24.9% (50/201) of dogs were positive in molecular diagnosis based on cathepsin L-marker.According to this study, it is necessary to implement a surveillance policy of visceral leishmaniasis, intensifying the actions of diagnosis, prevention, and control of this zoonosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32522138/