Peer-reviewed veterinary case report
How thyroid hormones and blood fats relate to leishmaniosis in dogs
By Khaleghi Einakchi, M et al.·Published in Parasitology research·2018·Department of Clinical Sciences·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Canine visceral leishmaniosis: the relationship of blood serum thyroid hormones, lipids, and lipoproteins with clinical status.
- Species:
- dog
Plain-English summary
A group of dogs with leishmaniasis, a serious infection caused by the Leishmania parasite, showed signs of illness and had lower levels of thyroid hormones and certain fats in their blood compared to healthy dogs. Specifically, the sick dogs had significantly reduced levels of total and free T4 thyroid hormones, as well as lower levels of good cholesterol (HDL-C). This suggests that changes in thyroid hormones and lipoproteins might affect how these dogs respond to the infection. Understanding these changes could help veterinarians better manage and treat dogs suffering from leishmaniasis.
People also search for: dog leishmaniasis symptoms · low thyroid in dogs · dog thyroid hormone treatment
Abstract
The objective of the present study was to investigate the role of thyroid hormones and lipid profile in development and outcome of canine visceral leishmaniosis (CVL). We therefore studied the relationships between blood serum thyroid hormones [total T4, free T4, total T3, and free T3], lipids, and lipoproteins [total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)] and clinical status in dogs naturally infected with Leishmania infantum. Two groups of Leishmania-infected dogs [with no clinical signs (NCS; n = 15), and with clinical signs (CS; n = 16)] were assessed and compared with a group of healthy control dogs (n = 15). A significant decrease in serum total T4 (p < 0.05) concentration in the CS group was observed when compared to the NCS and control groups. The dogs in CS group revealed a significant decrease (p < 0.05) in free T4 concentration in comparison to the control group. The CS group presented a significant decrease in HDL-C (p < 0.01) concentrations, when compared to NCS and control groups. The observed findings in the present study suggested that thyroid hormone and lipoprotein alterations may have a role in susceptibility of dogs with Leishmania infection.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30264326/